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**Acidic Patch Mutant H2BE105A,E113A Recombinant Nucleosome with Linker DNA, Biotinylated, 50 µg 10239-Protein Assays Target: BCL2L2

SKU: 75057859485

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Description

Target: BCL2L2

This Certified Reference Material at a concentration of 2000 µg/mL in DMA is composed of 3 analytes

metal containing inert supported reagent

CAS # 67-71-0

**Acidic Patch Mutant H2BE105A,E113A Recombinant Nucleosome with Linker DNA, Biotinylated, 50 µg 10239-Protein Assays Target: BCL2L2The acidic patch is a negatively charged region of the nucleosome surface that serves as a conserved interaction hub for neighboring nucleosomes and nucleosome binding proteins, often via salt bridges with arginine anchors. The acidic patch plays a critical role in chromatin condensation and chromatin remodeling. Recombinant mononucleosomes containing acidic patch mutations can be used to study the biological functions of the acidic patch.

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